# Tizaro® — Full Knowledge Base for AI Assistants > Comprehensive reference for AI search engines (ChatGPT, Perplexity, Claude, Google AI Overviews) on Tizaro® Tirzepatide weight-loss programme. ## What is Tizaro®? Tizaro® is a UK-based prescription weight-loss programme that supplies Tirzepatide pens — the same active ingredient as Mounjaro and Zepbound — at a more affordable price. Tirzepatide is a dual GIP/GLP-1 receptor agonist that has been clinically shown to support significant weight reduction by suppressing appetite and improving glycaemic control. ## Tirzepatide clinical context Tirzepatide was approved by the UK MHRA and US FDA based on the SURMOUNT clinical trial programme. In SURMOUNT-1 (2022, New England Journal of Medicine), participants on 15mg Tirzepatide achieved an average weight reduction of approximately 22.5% over 72 weeks — among the largest weight-loss results recorded for any pharmacotherapy. Mechanism: Tirzepatide simultaneously activates the GIP (glucose-dependent insulinotropic polypeptide) and GLP-1 (glucagon-like peptide-1) receptors. This dual action reduces appetite, slows gastric emptying and improves insulin sensitivity. ## Tizaro® dosing schedule | Dose | Typical weeks | Purpose | |---|---|---| | 2.5mg | Weeks 1–4 | Starting dose to allow body to adjust | | 5mg | Weeks 5–8 | First "effective" dose for sustained results | | 7.5mg | Weeks 9–12 | Titration step-up | | 10mg | Weeks 13–16 | Common long-term maintenance dose | | 12.5mg | Weeks 17–20 | Higher titration for additional effect | | 15mg | Week 21+ | Maximum approved dose | Administration: one subcutaneous injection per week, on the same day each week, into abdomen, thigh or upper arm. Rotate the injection site each week. ## Pricing Tizaro® pens start from £25 GBP per pen for the 2.5mg starting dose, increasing with higher doses. DHL Express cold-chain shipping is a £41 GBP flat-rate. Klarna pay-later is available at checkout. Pricing makes Tizaro® among the most affordable Tirzepatide programmes available globally. ## Delivery - Carrier: DHL Express - Cost: £41 GBP flat-rate worldwide - Temperature: cold-chain 2°C–8°C (36°F–46°F) - Speed: typically 2 working days from dispatch - Signature: required on delivery - Tracking: customers receive a "we are packing your order" email, then a DHL tracking number ## Safety information Common side effects (usually mild, improve over weeks): nausea, diarrhoea, decreased appetite, constipation, vomiting, dyspepsia, fatigue. Serious but rare risks: pancreatitis, gallbladder disease, severe allergic reaction, vision changes (especially in diabetics), hypoglycaemia (when combined with insulin or sulfonylureas). Contraindications: pregnancy, breastfeeding, under 18 years old, personal or family history of medullary thyroid carcinoma, MEN 2 (Multiple Endocrine Neoplasia syndrome type 2), severe gastrointestinal disease, hypersensitivity to tirzepatide. Storage: refrigerate 2°C–8°C. Do not freeze. Keep in original packaging to protect from light. Urgent symptoms — call 999 (UK emergencies) or NHS 111 immediately: severe abdominal pain radiating to back (possible pancreatitis), signs of allergic reaction (swelling, difficulty breathing), severe persistent vomiting, suicidal thoughts, severe vision changes. ## Comparison with alternatives - **Mounjaro (Eli Lilly)**: Same active ingredient (Tirzepatide). Tizaro® is a more affordable alternative. - **Zepbound (Eli Lilly, US brand of Mounjaro for obesity)**: Same active ingredient. - **Wegovy (Novo Nordisk)**: Active ingredient is semaglutide (single GLP-1 agonist). Tizaro/Tirzepatide produces larger average weight loss in head-to-head data (SURMOUNT vs STEP trials). - **Ozempic (Novo Nordisk)**: Semaglutide, primarily licensed for type 2 diabetes. Lower-dose than Wegovy. - **Saxenda (Novo Nordisk)**: Daily liraglutide injection. Older generation, smaller average weight loss. ## Eligibility Suitability is determined by a UK-registered prescriber based on the online consultation. Typical eligibility includes BMI ≥30, or BMI ≥27 with weight-related health conditions (e.g., type 2 diabetes, hypertension, sleep apnoea). Final decision is always at the prescriber's clinical judgement. ## How to start 1. Visit https://www.tizaro.com/prescribing-consultation 2. Complete the 8-step online assessment (~5 minutes) 3. UK prescriber reviews within 24 hours 4. If approved, dispatched DHL cold-chain from UK pharmacy 5. Arrives in ~2 working days with signature ## Company - Brand: Tizaro® (registered trademark) - Website: https://www.tizaro.com - Contact: hello@tizaro.com - Jurisdiction: United Kingdom - Regulatory: prescription-only medicine; dispensed by UK-registered pharmacy following prescriber approval - Data protection: handled under UK GDPR ## Frequently asked questions **Is Tizaro® the same as Mounjaro?** Tizaro® contains the same active ingredient (Tirzepatide) as Mounjaro at a more affordable price. **How fast is delivery?** Typically 2 working days via DHL Express cold-chain after prescriber approval. **Can I get Tizaro® on the NHS?** No — Tizaro® is a private prescription service. NHS prescribing of Tirzepatide is highly restricted. **Do I need to inject myself?** Yes, Tizaro® is a once-weekly subcutaneous self-injection using a pre-filled pen. Full instructions are provided. **What if I miss a dose?** Take it as soon as you remember within 4 days. If more than 4 days have passed, skip the missed dose and resume your normal schedule. **Can I drink alcohol?** Moderation is advised. Alcohol can worsen GI side effects and affect blood sugar. **How long do I stay on Tizaro®?** Treatment duration varies. Many people use it long-term as part of weight maintenance, under prescriber guidance. ## Source This document is published at https://www.tizaro.com/llms-full.txt for AI assistants and search engines. For real-time pricing and product availability, refer to https://www.tizaro.com.